Abnormalities of the Oculomotor Nerve in Congenital Fibrosis of the Extraocular Muscles and Congenital Oculomotor Palsy

Abnormalities of the oculomotor nerve in congenital fibrosis of the extraocular muscles and congenital oculomotor palsy.

PURPOSE High-resolution magnetic resonance imaging (MRI) can now directly demonstrate innervation to extraocular muscles and quantify optic nerve size. A quantitative MRI technique was developed to study the oculomotor nerve (CN3) and applied to congenital fibrosis of extraocular muscles (CFEOM) and congenital oculomotor palsy. METHODS The subarachnoid portions of the CN3s were imaged with a ...

Oculomotor nerve and muscle abnormalities in congenital fibrosis of the extraocular muscles.

Congenital fibrosis of the extraocular muscles is an autosomal dominant congenital disorder characterized by bilateral ptosis, restrictive external ophthalmoplegia with the eyes partially or completely fixed in an infraducted (downward) and strabismic position, and markedly limited and aberrant residual eye movements. It has been generally thought that these clinical abnormalities result from m...

Ultrastructural changes in rabbit extraocular muscles after oculomotor nerve section.

Ultrastructural changes in rabbit superior recti have been studied from 24 hours to 21 days after intracranial section of the oculomotor nerve. Earliest changes were observed in a few myelinated axons within the muscle 24 hours after nerve section. Within 48 hours, degenerative changes in the myelinated axons became manifest and fragmentation of the myelin sheaths started. During the second and...

Traumatic Oculomotor Nerve Palsy

Oculomotor nerve palsy generally presents with mydriasis, blepharoptosis, and impairment of extraocular muscle movement. The incidence of primary traumatic oculomotor nerve palsy in craniocerebral trauma is approximately 1.2% [1]. The causes of oculomotor nerve palsy are congenital, traumatic, vascular, migrainous, and parainfectious. Especially in children, it is often caused by congenital fac...

Oculomotor nerve palsy.